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Recommended system requirements:

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The latest Prism version is 9.2.0 (Windows and Mac).

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Update for free by downloading the Prism 9 installer for your system (instructions):

Windows | Mac

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Contact us at help.graphpad.com to learn about upgrade options.

Prism 9.2.0

July 20, 2021

This release introduces a variety of improvements:

• Searchable analyses in the Analyze Data dialog for faster access
• Graphs with improved snapping behavior of axis titles
• Graph Portfolio with new color schemes and other improvements
• And many more enhancements

Prism 9.1.2

June 2, 2021

This release fixes multiple issues in Prism 9.1.1. See full list

Prism 9.1.1

May 11, 2021

This release fixes multiple issues in Prism 9.1.0. See full list

Prism 9.1.0

March 17, 2021

Introducing exclusive learning resources for subscribers, and many analysis improvements:

• Prism Academy & Intuitive Biostatistics: Access over 125 video lessons taught by highly-technical experts, and the popular Intuitive Biostatistics e-book — free with your Prism subscription, and accessible from the Welcome dialog and Help menu
• New Analyze menu that makes it easier to find the analyses you need (searchable on macOS)
• Principal Component Analysis graphs with a single selected principal component (same component on both axes)
• And many more enhancements

Prism 9.0.2

February 17, 2021

This release fixes multiple issues in Prism 9.0.1. See full list

Prism 9.0.1

January 26, 2021

This release introduces support for the Apple M1 (ARM) chipset, and fixes multiple issues in Prism 9.0.0. See full list

Prism 9: Taking your analyses and graphs to higher dimensions

October 28, 2020

This major release brings highly requested new features and capabilities, including:

• Automatic Stars on Graphs: add multiple comparison results to graphs instantly
• Principal Component Analysis (PCA)
• Bubble Plots from multiple variables data
• Estimation Plots from t-tests
• Text in Multiple Variables tables and automatic identification of variable types (continuous, categorical, labels)
• Multiple t-test options: paired, nonparametric and more
• Interpolation from Multiple Linear and Multiple Logistic Regression
• Increased data limits
• And many more improved analyses

Prism 8.4.3

June 17, 2020

This release fixes multiple issues in Prism 8.4.2, and improves the support experience. See full list

Prism 8.4.2

April 13, 2020

This release fixes multiple bugs in Prism 8.4.1. See full list

Prism 8.4.1

March 23, 2020

This release fixes multiple graphing issues in Prism 8.4.0. See full list

Prism 8.4.0

March 4, 2020

Introducing a new look for violin plots, confidence bands for logistic regression, brand new color schemes (including heat map colormaps), and more:

• The option to display full - or truncated - violin plots
• Confidence intervals reported for X at Y=50 for Simple Logistic Regression
• The ability to plot confidence bands for the logistic curve from Simple and Multiple Logistic Regression
• Colormaps 'Viridis', 'Magma', 'Inferno', and 'Plasma' added for heat maps (Viridis now the default)
• Color schemes inspired by 'Viridis', 'Magma', 'Inferno', and 'Plasma' added for other types of graphs
• Added analytical representation of the 'Two-phase decay' exponential built-in equation
• The ability to generate a graph after performing the Normalize analysis on any type of data table
• And many additional performance improvements and bug fixes

Prism 8.3.1

January 20, 2020

This release fixes multiple issues in Prism 8.3.0, and improves stability. See full list

Prism 8.3.0

October 29, 2019

Introducing Logistic Regression: model binary probability (e.g. yes/no, pass/fail) with a single or multiple explanatory variables. Included in this release:

• New simple logistic regression analysis in XY data tables
• New multiple logistic regression analysis in Multiple Variables data tables
• Improved support for macOS Catalina
• Added analytical representations of polynomial functions (5th, 6th, and 10th order)
• Improved auto-recovery of Prism files under specific situations
• And many additional performance improvements and bug fixes

Prism 8.2.1

August 28, 2019

This release fixes multiple issues in Prism 8.2.0, and improves stability. See full list

Prism 8.2.0

July 22, 2019

Introducing new features, performance improvements and bug fixes for Prism 8, including:

• New options for visualizing scatter plots. Choose from three different styles and set your preferred style as a default
• New equations in the nonlinear regression equation library: Absolute IC50 and all dose-response equations with X as concentration OR log(concentration)
• The option to set a graph's axis scale to a Natural Log (Ln) scale
• The ability to add multiple annotations for a single bar (above, within at top, AND within at bottom)
• The option to toggle between a 'Data with Results' view in the Navigator (data tables and linked results sheets grouped), or separate 'Data' and 'Results' sections
• Improved Results Tabs appearance, increasing visibility and usability
• Expanded results from ordinary Two-way ANOVA, now including a 'Data summary' section displaying a number of columns, rows, and values
• Corrected results for repeated measures Two-way ANOVA when no variation between subjects exists
• The ability to export semi-transparent objects on a graph to PDF

Also, introducing Prism Labs with the first release from our experimental workshop: explore how Prism can now identify 'unstable' parameters in nonlinear regression instead of classifying entire model fits as 'ambiguous'. Learn more

Prism 8.1.2

May 28, 2019

This release fixes multiple issues in Prism 8.1.1, including fixing 'multiple comparisons' results in Two-way ANOVA when entering data as SD/SEM/CV and N. See full list

Prism 8.1.1

April 25, 2019

This release fixes multiple issues in Prism 8.1.0, including fixing 'multiple comparisons' results when comparing cell means in Two-way ordinary balanced ANOVA. See full list

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Prism 8.1.0

April 3, 2019

Introducing new features, performance improvements and bug fixes for Prism 8, including:

• New (and useful!) color schemes, including a color-blind safe palette. Learn more ›
• Automatic color selection for annotations and labels for better contrast in graphs.
• Correlation matrix analysis now generates a heatmap of R² values.
• Option to calculate profile likelihood CIs with ambiguous fits.
• 'Dunnett T3' test to compare the mean of each column with the mean of every other column after nonparametric one-way ANOVA.
• Improved scatterplot appearance.

Prism 8.0.2

February 6, 2019

This release includes over 80 bug fixes for Prism 8, including performance and stability improvements. See full list

Prism 8.0.1

December 5, 2018

This release includes over 50 bug fixes for Prism 8, including performance and stability improvements. See full list

Prism 8.0.0

October 16, 2018

Prism 8 introduces brand new ways to organize, analyze, and graph your data, all while making the process easier and more intuitive. Powerful new analyses and graph styles provide more ways than ever to process and present your data, while familiar features have received comprehensive improvements to enhance and streamline your work. Despite all the changes, Prism is still Prism so you can be productive right away.

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• Mixed effects model for analysis of repeated measures ANOVA with missing data.
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Prism 7.05/e

August 27, 2018

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• Improved the algorithm used by the Dunnett test when the sample sizes are unequal.
• Fixed bug in some results of the test for linear trend following repeated measures one-way ANOVA.
• Improved auto-recovering feature so that Prism does not crash when opening slightly damaged Prism files.
• Update notifications to stay up-to-date.
• Support for seamless subscription renewals without requiring reactivation.
• And many other bugs fixes.

Release notes: Windows, Mac